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Zuletzt aktualisiert: 2022-05-31 20:57:59
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| Rehli Lab Home (current) Research People Publications Resources For Students Useful Links Materials Track Hubs Motifs Seminars Lab Seminar Journal Club Bioinformatics Mononuclear Phagocyte Biology Epigenetics of Cell Differentiation Epigenetics & Gene Regulation Although every cell in the human body shares an identical genome, most genes are only activated in certain cell types, at specific developmental stages, or upon stimulation. To organize and manage genetic information and to enable cellular specification, nature has evolved sophisticated mechanisms that facilitate the tightly controlled, accurate activation of genes. Our laboratory is interested in the processes that orchestrate cell type-specific gene regulation during cellular differentiation. We study the interplay between transcription factors and epigenetic mechanisms (in particular DNA methylation) in regulating hematopoietic lineage specification and leukemia development. Read more Featured Content News (March 2021) |